Hepatitis A: Clinical, Epidemiological and Molecular Characteristics
نویسنده
چکیده
Hepatitis A virus (HAV) is a member of the Hepatovirus genus of Picornaviridae family. HAV is a non-enveloped (naked), linear, single stranded RNA virus of an icosahedral symmetry measuring 27-32 nm in diameter (Feinstone, 1973). The infectious particle consists of capsid protein and RNA genome (Fig. 1). The buoyant density of the mature particle is 1.33g/cm3 in CsCl solutions and the sedimentation coefficient is 160S in sucrose solutions (Ticehurst, 1983).
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تاریخ انتشار 2012